Emerging roles of SIRT1 activator, SRT2104, in disease treatment

Emerging roles of SIRT1 activator, SRT2104, in disease treatment

Abstract Silent information regulator 1 (SIRT1) is a NAD+-dependent class III deacetylase that plays important roles in the pathogenesis of numerous diseases, positioning it as a prime candidate for therapeutic intervention. Among its modulators, SRT2104 emerges as the most specific small molecule a...

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Bibliographic Details
Main Authors: Ning Chang, Junyang Li, Sufen Lin, Jinfeng Zhang, Weiqiang Zeng, Guoda Ma, Yajun Wang
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Scientific Reports
Subjects:
SRT2104
SIRT1
Disease treatment
Preclinical research
Clinical trials
Online Access:https://doi.org/10.1038/s41598-024-55923-8

Internet

https://doi.org/10.1038/s41598-024-55923-8

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