MIA SH3 Domain ER Export Factor 3 Deficiency Prevents Neointimal Formation by Restoring BAT-Like PVAT and Decreasing VSMC Proliferation and Migration

MIA SH3 Domain ER Export Factor 3 Deficiency Prevents Neointimal Formation by Restoring BAT-Like PVAT and Decreasing VSMC Proliferation and Migration

Abnormal proliferation and migration of vascular smooth muscle cells (VSMCs) and excessive accumulation of dysfunctional PVAT are hallmarks of pathogenesis after angioplasty. Recent genome-wide association studies reveal that single-nucleotide polymorphism (SNP) in MIA3 is associated with atheroscle...

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Bibliographic Details
Main Authors: Yu Lei, Jianfei Xu, Mengju Li, Ting Meng, Meihua Chen, Yongfeng Yang, Hongda Li, Tao Zhuang, Junli Zuo
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Endocrinology
Subjects:
PVAT
MIA3
VSMCs
neointima
adipocytes
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.748216/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2021.748216/full

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