Non-catalytic roles for TET1 protein negatively regulating neuronal differentiation through srGAP3 in neuroblastoma cells

Non-catalytic roles for TET1 protein negatively regulating neuronal differentiation through srGAP3 in neuroblastoma cells

ABSTRACT The methylcytosine dioxygenases TET proteins (TET1, TET2, and TET3) play important regulatory roles in neural function. In this study, we investigated the role of TET proteins in neuronal differentiation using Neuro2a cells as a model. We observed that knockdown of TET1, TET2 or TET3 promot...

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Bibliographic Details
Main Authors: Jie Gao, Yue Ma, Hua-Lin Fu, Qian Luo, Zhen Wang, Yu-Huan Xiao, Hao Yang, Da-Xiang Cui, Wei-Lin Jin
Format: Article
Language:English
Published: Oxford University Press 2016-04-01
Series:Protein & Cell
Subjects:
methylcytosine dioxygenase
TET1
srGAP3
neuronal differentiation
neuroblastoma cells
Online Access:http://link.springer.com/article/10.1007/s13238-016-0267-4

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http://link.springer.com/article/10.1007/s13238-016-0267-4

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