GLP-1 attenuates intestinal fat absorption and chylomicron production via vagal afferent nerves originating in the portal vein
Background/Objective: GLP-1R agonists have been shown to reduce fasting and postprandial plasma lipids, both of which are independent risk factors for the development of cardiovascular disease. However, how endogenous GLP-1 – which is rapidly degraded – modulates intestinal and hepatic lipid metabol...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-11-01
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Series: | Molecular Metabolism |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2212877822001594 |