Rif1: a conserved regulator of DNA replication and repair hijacked by telomeres in yeasts

Rif1 was originally identified in the budding yeast S. cerevisiae as a telomere-binding protein that negatively regulates telomerase-mediated telomere elongation. Although this function is conserved in the distantly related fission yeast S. pombe, recent studies, both in yeasts and in metazoans, rev...

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Bibliographic Details
Main Authors: Stefano eMattarocci, Lukas eHafner, Aleksandra eLezaja, Maksym eShyian, David eShore
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-03-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2016.00045/full