Hemoglobin is an oxygen-dependent glutathione buffer adapting the intracellular reduced glutathione levels to oxygen availability

Hemoglobin is an oxygen-dependent glutathione buffer adapting the intracellular reduced glutathione levels to oxygen availability

Fast changes in environmental oxygen availability translate into shifts in mitochondrial free radical production. An increase in intraerythrocytic reduced glutathione (GSH) during deoxygenation would support the detoxification of exogenous oxidants released into the circulation from hypoxic peripher...

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Bibliographic Details
Main Authors: Simone Fenk, Elizaveta V. Melnikova, Anastasia A. Anashkina, Yuri M. Poluektov, Pavel I. Zaripov, Vladimir A. Mitkevich, Yaroslav V. Tkachev, Lars Kaestner, Giampaolo Minetti, Heimo Mairbäurl, Jeroen S. Goede, Alexander A. Makarov, Irina Yu Petrushanko, Anna Bogdanova
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S221323172200307X

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http://www.sciencedirect.com/science/article/pii/S221323172200307X

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