Research progress in the establishment of pancreatic cancer models and preclinical applications

Abstract Pancreatic cancer (PC) is a highly malignant tumor in the digestive system. The transformation of tissue from normal to pancreatic intraepithelial neoplasm is driven by certain oncogenes, among which the mutation rate of the KRAS gene is as high as 90%. Currently, PC has limited treatment o...

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Bibliographic Details
Main Authors: Weizheng Wu, Kunming Wen, Yuxin Zhong
Format: Article
Language:English
Published: Wiley 2022-10-01
Series:Cancer Innovation
Subjects:
Online Access:https://doi.org/10.1002/cai2.31