Stimulation Through CD40 and TLR-4 is an Effective Host Directed Therapy Against Mycobacterium tuberculosis

AbstractTuberculosis (TB) is the leading cause of morbidity and mortality among all infectious diseases. Failure of Bacillus Calmette Guerin (BCG) as a vaccine and serious side effects and toxicity due to long-term TB drug regime are the major hurdles associated with TB control. The problem is furth...

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Bibliographic Details
Main Authors: Nargis Khan, Susanta Pahari, Aurobind Vidyarthi, Mohammad Aqdas, Javed Naim Agrewala
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-09-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00386/full