Knockdown of interleukin‐6 plays a neuroprotective role against hypoxia‐ischemia in neonatal rats via inhibition of caspase 3 and Bcl‐2‐associated X protein signaling pathway

Abstract This study aimed to investigate the role of interleukin‐6 (IL‐6) in the pathogenesis of neonatal hypoxic‐ischemic encephalopathy (NHIE). Sprague‐Dawley (SD) rats were used for the establishment of hypoxic‐ischemic (HI) model. The Zea‐Longa scoring was used to evaluate the extent of the neur...

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Bibliographic Details
Main Authors: Xiu Yang, Ke‐Han Liao, Isaac B. Deng, Lan‐Chun Zhang
Format: Article
Language:English
Published: Wiley-VCH 2022-09-01
Series:Ibrain
Subjects:
Online Access:https://doi.org/10.1002/ibra.12067