SIRT2 gene has a classic SRE element, is a downstream target of serum response factor and is likely activated during serum stimulation.

The sirtuin proteins are an evolutionarily conserved family of NAD+-dependent deacetylases that regulate various cellular functions. Among the seven sirtuins, SIRT2 is predominantly found in the cytoplasm, and is present in a wide range of tissues. Recent studies indicate that SIRT2 plays an importa...

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Bibliographic Details
Main Authors: Xiaomin Zhang, Gohar Azhar, Jeanne Y Wei
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5739444?pdf=render