Investigating the Role of TGF-β Signaling Pathways in Human Corneal Endothelial Cell Primary Culture

Investigating the Role of TGF-β Signaling Pathways in Human Corneal Endothelial Cell Primary Culture

Corneal endothelial diseases are the leading cause of corneal transplantation. The global shortage of donor corneas has resulted in the investigation of alternative methods, such as cell therapy and tissue-engineered endothelial keratoplasty (TEEK), using primary cultures of human corneal endothelia...

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Bibliographic Details
Main Authors: Inès Aouimeur, Tomy Sagnial, Louise Coulomb, Corantin Maurin, Justin Thomas, Pierre Forestier, Sandrine Ninotta, Chantal Perrache, Fabien Forest, Philippe Gain, Gilles Thuret, Zhiguo He
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Cells
Subjects:
corneal transplantation
corneal endothelial cells (CECs)
TGF-β
endothelial–mesenchymal transition (EndMT)
endothelial cell density (ECD)
cell therapy
Online Access:https://www.mdpi.com/2073-4409/12/12/1624

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https://www.mdpi.com/2073-4409/12/12/1624

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