Desmocollin-1 is associated with pro-metastatic phenotype of luminal A breast cancer cells and is modulated by parthenolide

Abstract Background Desmocollin-1 (DSC1) is a desmosomal transmembrane glycoprotein that maintains cell-to-cell adhesion. DSC1 was previously associated with lymph node metastasis of luminal A breast tumors and was found to increase migration and invasion of MCF7 cells in vitro. Therefore, we focuse...

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Bibliographic Details
Main Authors: Petr Lapcik, Petr Sulc, Lucia Janacova, Katerina Jilkova, David Potesil, Pavla Bouchalova, Petr Müller, Pavel Bouchal
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Cellular & Molecular Biology Letters
Subjects:
Online Access:https://doi.org/10.1186/s11658-023-00481-6