Engineered extracellular vesicles for delivery of siRNA promoting targeted repair of traumatic spinal cord injury

Engineered extracellular vesicles for delivery of siRNA promoting targeted repair of traumatic spinal cord injury

Spinal cord injury (SCI) is a severe disease of the nervous system that causes irreparable damage and loss of function, for which no effective treatments are available to date. Engineered extracellular vesicles (EVs) carrying therapeutic molecules hold promise as an alternative SCI therapy depending...

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Bibliographic Details
Main Authors: Yuluo Rong, Zhuanghui Wang, Pengyu Tang, Jiaxing Wang, Chengyue Ji, Jie Chang, Yufeng Zhu, Wu Ye, Jianling Bai, Wei Liu, Guoyong Yin, Lipeng Yu, Xuhui Zhou, Weihua Cai
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-05-01
Series:Bioactive Materials
Subjects:
Extracellular vesicles
Spinal cord injury
siRNA
Microglia/macrophages polarization
Induced neural stem cells
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X22004753

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http://www.sciencedirect.com/science/article/pii/S2452199X22004753

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