In vitro activity of human defensins HNP-1 and hBD-3 against multidrug-resistant ESKAPE Gram-negatives of clinical origin and selected peptidoglycan recycling-defective mutants

In vitro activity of human defensins HNP-1 and hBD-3 against multidrug-resistant ESKAPE Gram-negatives of clinical origin and selected peptidoglycan recycling-defective mutants

ABSTRACTThe use of immune compounds as antimicrobial adjuvants is a classic idea recovering timeliness in the current antibiotic resistance scenario. However, the activity of certain antimicrobial peptides against ESKAPE Gram-negatives has not been sufficiently investigated. The objective of this st...

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Bibliographic Details
Main Authors: María Escobar-Salom, Isabel María Barceló, Estrella Rojo-Molinero, Elena Jordana-Lluch, Gabriel Cabot, Antonio Oliver, Carlos Juan
Format: Article
Language:English
Published: American Society for Microbiology 2024-04-01
Series:Microbiology Spectrum
Subjects:
ESKAPE Gram-negatives
Pseudomonas aeruginosa
Klebsiella pneumoniae
Enterobacter cloacae complex
Acinetobacter baumannii
Human Neutrophil Peptide-1 (HNP-1)
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00358-24

Internet

https://journals.asm.org/doi/10.1128/spectrum.00358-24

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