Smilax china L. Polysaccharide Alleviates Oxidative Stress and Protects From Acetaminophen-Induced Hepatotoxicity via Activating the Nrf2-ARE Pathway

Smilax china L. Polysaccharide Alleviates Oxidative Stress and Protects From Acetaminophen-Induced Hepatotoxicity via Activating the Nrf2-ARE Pathway

The alleviation of oxidative stress is considered an effective treatment for acetaminophen (APAP)-induced acute liver injury (AILI). However, it remains unknow whether the potential antioxidant Smilax china L. polysaccharide (SCLP) protects against AILI. In this study, in vitro and in vivo experimen...

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Bibliographic Details
Main Authors: Kaiping Wang, Linlin Yang, Jing Zhou, Xianglin Pan, Zihao He, Junxi Liu, Yu Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Pharmacology
Subjects:
Nrf2-ARE.
acetaminophen
oxidative stress
acute liver injury
Smilax china L. polysaccharide
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.888560/full

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https://www.frontiersin.org/articles/10.3389/fphar.2022.888560/full

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