Immobilized Bisphosphonates as Potential Inhibitors of Bioprosthetic Calcification: Effects on Various Xenogeneic Cardiovascular Tissues

Immobilized Bisphosphonates as Potential Inhibitors of Bioprosthetic Calcification: Effects on Various Xenogeneic Cardiovascular Tissues

Calcification is the major factor limiting the clinical use of bioprostheses. It may be prevented by the immobilization of bisphosphonic compounds (BPs) on the biomaterial. In this study, we assessed the accumulation and structure of calcium phosphate deposits in collagen-rich bovine pericardium (Pe...

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Bibliographic Details
Main Authors: Irina Y. Zhuravleva, Anna A. Dokuchaeva, Elena V. Karpova, Tatyana P. Timchenko, Anatoly T. Titov, Svetlana S. Shatskaya, Yuliya F. Polienko
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Biomedicines
Subjects:
bioprosthetic calcification
bisphosphonate
porcine aortic wall
bovine jugular vein
cross-linking
glutaraldehyde
Online Access:https://www.mdpi.com/2227-9059/10/1/65

Internet

https://www.mdpi.com/2227-9059/10/1/65

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