Antibodies Enhance the Suppressive Activity of Extracellular Vesicles in Mouse Delayed-Type Hypersensitivity

Antibodies Enhance the Suppressive Activity of Extracellular Vesicles in Mouse Delayed-Type Hypersensitivity

Previously, we showed that mouse delayed-type hypersensitivity (DTH) can be antigen-specifically downregulated by suppressor T cell-derived miRNA-150 carried by extracellular vesicles (EVs) that target antigen-presenting macrophages. However, the exact mechanism of the suppressive action of miRNA-15...

Full description

Bibliographic Details
Main Authors: Katarzyna Nazimek, Eugenio Bustos-Morán, Noelia Blas-Rus, Bernadeta Nowak, Justyna Totoń-Żurańska, Michał T. Seweryn, Paweł Wołkow, Olga Woźnicka, Rafał Szatanek, Maciej Siedlar, Philip W. Askenase, Francisco Sánchez-Madrid, Krzysztof Bryniarski
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Pharmaceuticals
Subjects:
antigen-presenting cells
antigen-specific T cell suppression
contact hypersensitivity
delayed-type hypersensitivity
extracellular vesicles
immune tolerance
Online Access:https://www.mdpi.com/1424-8247/14/8/734

Internet

https://www.mdpi.com/1424-8247/14/8/734

Similar Items