Whole exome sequencing reveals genetic landscape associated with left ventricular outflow tract obstruction in Chinese Han population

Left ventricular outflow tract obstruction (LVOTO), a major form of outflow tract malformation, accounts for a substantial portion of congenital heart defects (CHDs). Unlike its prevalence, the genetic architecture of LVOTO remains largely unknown. To unveil the genetic mutations and risk genes pote...

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Bibliographic Details
Main Authors: Zilong Geng, Wenjuan Li, Ping Yang, Shasha Zhang, Shuo Wu, Junhao Xiong, Kun Sun, Dan Zhu, Sun Chen, Bing Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1267368/full