Telmisartan versus metformin in downregulating myostatin gene expression and enhancing insulin sensitivity in the skeletal muscles of type 2 diabetic rat model

Telmisartan versus metformin in downregulating myostatin gene expression and enhancing insulin sensitivity in the skeletal muscles of type 2 diabetic rat model

Objective: Telmisartan is an angiotensin receptor blocker (ARB) that specifically blocks angiotensin II type-1 receptors (AT1R). Telmisartan has been proven to have antidiabetic effects via a variety of mechanisms, and it can be utilized in some diabetic patients due to its dual benefit for hyperten...

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Bibliographic Details
Main Authors: Ahmed Abd-Eltawab Tammam, Waleed Y. Rizg, Amy Fakhry Boushra, Maha Alhelf, Mohammed Alissa, Ghada F. Soliman, Ghada Nady Ouais, Khaled M. Hosny, Hala M. Alkhalidi, Ahmed Magdy Elebiary
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Pharmacology
Subjects:
antidiabetic drugs
insulin resistance
metformin
myostatin
telmisartan
type 2 DM
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1228525/full

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https://www.frontiersin.org/articles/10.3389/fphar.2023.1228525/full

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