Thalamic nucleus reuniens coordinates prefrontal-hippocampal synchrony to suppress extinguished fear

Abstract Traumatic events result in vivid and enduring fear memories. Suppressing the retrieval of these memories is central to behavioral therapies for pathological fear. The medial prefrontal cortex (mPFC) and hippocampus (HPC) have been implicated in retrieval suppression, but how mPFC-HPC activi...

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Bibliographic Details
Main Authors: Michael S. Totty, Tuğçe Tuna, Karthik R. Ramanathan, Jingji Jin, Shaun E. Peters, Stephen Maren
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-42315-1