Spatial control of neuronal metabolism through glucose-mediated mitochondrial transport regulation

Eukaryotic cells modulate their metabolism by organizing metabolic components in response to varying nutrient availability and energy demands. In rat axons, mitochondria respond to glucose levels by halting active transport in high glucose regions. We employ quantitative modeling to explore physical...

Full description

Bibliographic Details
Main Authors: Anamika Agrawal, Gulcin Pekkurnaz, Elena F Koslover
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-12-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/40986