Differential Expression of Mitochondrial Biogenesis Markers in Mouse and Human SHH-Subtype Medulloblastoma

Differential Expression of Mitochondrial Biogenesis Markers in Mouse and Human SHH-Subtype Medulloblastoma

Medulloblastoma is a brain tumor that arises predominantly in infants and children. It is the most common pediatric brain malignancy. Around 25% of medulloblastomas are driven by constitutive activation of the Hedgehog signaling pathway. Hedgehog-driven medulloblastoma is often studied in the labora...

Full description

Bibliographic Details
Main Authors: Maria Łastowska, Agnieszka Karkucińska-Więckowska, James A. Waschek, Paweł Niewiadomski
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Cells
Subjects:
medulloblastoma
Sonic hedgehog
Shh
oxidative phosphorylation
mitochondria
glycolysis
Warburg effect
gene expression
mouse model
Online Access:http://www.mdpi.com/2073-4409/8/3/216

Internet

http://www.mdpi.com/2073-4409/8/3/216

Similar Items