Anthrax immune globulin improves hemodynamics and survival during B. anthracis toxin-induced shock in canines receiving titrated fluid and vasopressor support

Anthrax immune globulin improves hemodynamics and survival during B. anthracis toxin-induced shock in canines receiving titrated fluid and vasopressor support

Abstract Background Although anthrax immune globulin (AIG) improved survival in antibiotic-treated Bacillus anthracis-challenged animal models, whether it adds to the benefit of conventional hemodynamic support for B. anthracis toxin-associated shock is unknown. Methods We therefore tested AIG in se...

Full description

Bibliographic Details
Main Authors: Dante A. Suffredini, Xizhong Cui, Dharmvir Jaswal, Kenneth E. Remy, Yan Li, Junfeng Sun, Steven B. Solomon, Yvonne Fitz, Mahtab Moayeri, Stephen Leppla, Peter Q. Eichacker
Format: Article
Language:English
Published: SpringerOpen 2017-10-01
Series:Intensive Care Medicine Experimental
Subjects:
B. anthracis
Anthrax infection
Anthrax immune globulin
Sepsis
Lethal toxin
Edema toxin
Online Access:http://link.springer.com/article/10.1186/s40635-017-0159-9

Internet

http://link.springer.com/article/10.1186/s40635-017-0159-9

Similar Items