Molecular signature incorporating the immune microenvironment enhances thyroid cancer outcome prediction

Molecular signature incorporating the immune microenvironment enhances thyroid cancer outcome prediction

Summary: Genomic and transcriptomic analysis has furthered our understanding of many tumors. Yet, thyroid cancer management is largely guided by staging and histology, with few molecular prognostic and treatment biomarkers. Here, we utilize a large cohort of 251 patients with 312 samples from two te...

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Bibliographic Details
Main Authors: George J. Xu, Matthew A. Loberg, Jean-Nicolas Gallant, Quanhu Sheng, Sheau-Chiann Chen, Brian D. Lehmann, Sophia M. Shaddy, Megan L. Tigue, Courtney J. Phifer, Li Wang, Mario W. Saab-Chalhoub, Lauren M. Dehan, Qiang Wei, Rui Chen, Bingshan Li, Christine Y. Kim, Donna C. Ferguson, James L. Netterville, Sarah L. Rohde, Carmen C. Solórzano, Lindsay A. Bischoff, Naira Baregamian, Aaron C. Shaver, Mitra Mehrad, Kim A. Ely, Daniel W. Byrne, Thomas P. Stricker, Barbara A. Murphy, Jennifer H. Choe, Luciane T. Kagohara, Elizabeth M. Jaffee, Eric C. Huang, Fei Ye, Ethan Lee, Vivian L. Weiss
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Cell Genomics
Subjects:
aggressive thyroid cancer
cancer-associated fibroblasts
tumor immune microenvironment
next-generation sequencing
molecular biomarkers
anaplastic thyroid carcinoma
Online Access:http://www.sciencedirect.com/science/article/pii/S2666979X23002239

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http://www.sciencedirect.com/science/article/pii/S2666979X23002239

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