A benchtop brain injury model using resected donor tissue from patients with Chiari malformation

A benchtop brain injury model using resected donor tissue from patients with Chiari malformation

The use of live animal models for testing new therapies for brain and spinal cord repair is a controversial area. Live animal models have associated ethical issues and scientific concerns regarding the predictability of human responses. Alternative models that replicate the 3D architecture of the ce...

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Bibliographic Details
Main Authors: Jacqueline A Tickle, Jon Sen, Christopher Adams, David N Furness, Rupert Price, Viswapathi Kandula, Nikolaos Tzerakis, Divya M Chari
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Neural Regeneration Research
Subjects:
biomaterial; chiari malformation; cerebellar slice; human tissue; injury model; neuroregeneration; organotypic; traumatic brain injury
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2023;volume=18;issue=5;spage=1057;epage=1061;aulast=Tickle

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2023;volume=18;issue=5;spage=1057;epage=1061;aulast=Tickle

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