Agent-based vs. equation-based multi-scale modeling for macrophage polarization.

Macrophages show high plasticity and result in heterogenic subpopulations or polarized states identified by specific cellular markers. These immune cells are typically characterized as pro-inflammatory, or classically activated M1, and anti-inflammatory, or alternatively activated M2. However, a mor...

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Bibliographic Details
Main Authors: Sarah B Minucci, Rebecca L Heise, Angela M Reynolds
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0270779&type=printable