Single-cell protein activity analysis reveals a novel subpopulation of chondrocytes and the corresponding key master regulator proteins associated with anti-senescence and OA progression

BackgroundOsteoarthritis (OA) is a prevalent senescence-related disease with substantial joint pain, loss of joint function, and cartilage degeneration. Because of the paucity of single-cell studies of OA and the gene dropout problem of single-cell RNA sequencing, it is difficult to acquire an in-de...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Zhao Guang, Zhang Min, Li Jun-Tan, Dou Tian-Xu, Gao Xiang
स्वरूप: लेख
भाषा:English
प्रकाशित: Frontiers Media S.A. 2023-03-01
श्रृंखला:Frontiers in Immunology
विषय:
ऑनलाइन पहुंच:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1077003/full