Interplay of membrane crosslinking and curvature induction by annexins

Abstract Efficient plasma membrane repair (PMR) is required to repair damage sustained in the cellular life cycle. The annexin family of proteins, involved in PMR, are activated by Ca2+ influx from extracellular media at the site of injury. Mechanistic studies of the annexins have been overwhelmingl...

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Bibliographic Details
Main Authors: Anna Mularski, Stine Lauritzen Sønder, Anne Sofie Busk Heitmann, Mayank Prakash Pandey, Himanshu Khandelia, Jesper Nylandsted, Adam Cohen Simonsen
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-26633-w