RNF4 and USP7 cooperate in ubiquitin-regulated steps of DNA replication

RNF4 and USP7 cooperate in ubiquitin-regulated steps of DNA replication

DNA replication requires precise regulation achieved through post-translational modifications, including ubiquitination and SUMOylation. These modifications are linked by the SUMO-targeted E3 ubiquitin ligases (STUbLs). Ring finger protein 4 (RNF4), one of only two mammalian STUbLs, participates in...

Full description

Bibliographic Details
Main Authors: Ya-Chu Chang, Kevin Lin, Ryan M. Baxley, Wesley Durrett, Liangjun Wang, Olivera Stojkova, Maximilian Billmann, Henry Ward, Chad L. Myers, Anja-Katrin Bielinsky
Format: Article
Language:English
Published: The Royal Society 2023-08-01
Series:Open Biology
Subjects:
STUbL
SUMO
ubiquitin
genome stability
RNF4
USP7
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsob.230068

Internet

https://royalsocietypublishing.org/doi/10.1098/rsob.230068

Similar Items