Computationally efficient mechanism discovery for cell invasion with uncertainty quantification.

Parameter estimation for mathematical models of biological processes is often difficult and depends significantly on the quality and quantity of available data. We introduce an efficient framework using Gaussian processes to discover mechanisms underlying delay, migration, and proliferation in a cel...

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Bibliographic Details
Main Authors: Daniel J VandenHeuvel, Christopher Drovandi, Matthew J Simpson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-11-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1010599