Distinct Cell-specific Roles of NOX2 and MyD88 in Epileptogenesis

Distinct Cell-specific Roles of NOX2 and MyD88 in Epileptogenesis

It is well established that temporal lobe epilepsy (TLE) is often related to oxidative stress and neuroinflammation. Both processes subserve alterations observed in epileptogenesis and ultimately involve distinct classes of cells, including astrocytes, microglia, and specific neural subtypes. For th...

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Bibliographic Details
Main Authors: Cayo Almeida, Renan Paschoalino Pongilio, Marília Inês Móvio, Guilherme Shigueto Vilar Higa, Rodrigo Ribeiro Resende, Jianxiong Jiang, Erika Reime Kinjo, Alexandre Hiroaki Kihara
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
epilepsy
neuroinflammatory diseases
temporal lobe
single-cell analysis
cre recombinase
adeno-associated virus
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.926776/full

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https://www.frontiersin.org/articles/10.3389/fcell.2022.926776/full

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