Prolonged Maternal Separation Reduces Anxiety State and Increases Compulsive Burying Activity in the Offspring of BALB/c Mice

Prolonged Maternal Separation Reduces Anxiety State and Increases Compulsive Burying Activity in the Offspring of BALB/c Mice

Background: The elevated plus maze (EPM) and the marble burying (MB) tests are common behavioral tests used for behavioral phenotyping in mouse models for neurodevelopmental disorders. However, the behavioral effects of maternal separation (MS), a standard paradigm for early life stress in animals,...

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Bibliographic Details
Main Authors: Qais Jarrar, Rami Ayoub, Kawther Alhussine, Khang Wen Goh, Said Moshawih, Chrismawan Ardianto, Bey Hing Goh, Long Chiau Ming
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Journal of Personalized Medicine
Subjects:
maternal separation
anxiety
compulsivity
adaptation
reproductive health
pregnancy
Online Access:https://www.mdpi.com/2075-4426/12/11/1921

Internet

https://www.mdpi.com/2075-4426/12/11/1921

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