Effects of Hypothermia and Allopurinol on Oxidative Status in a Rat Model of Hypoxic Ischemic Encephalopathy

Effects of Hypothermia and Allopurinol on Oxidative Status in a Rat Model of Hypoxic Ischemic Encephalopathy

Hypoxic ischemic encephalopathy (HIE) is one of the main causes of morbidity and mortality during the neonatal period, despite treatment with hypothermia. There is evidence that oxidative damage plays an important role in the pathophysiology of hypoxic-ischemic (HI) brain injury. Our aim was to inve...

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Bibliographic Details
Main Authors: Cristina Durán Fernández-Feijóo, Javier Rodríguez-Fanjul, Miriam Lopez-Abat, Stephanie Hadley, Mónica Cavia-Saiz, Pilar Muñiz, Juan Arnaez, José Ramón Fernández-Lorenzo, Marta Camprubí Camprubí
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Antioxidants
Subjects:
allopurinol
hypothermia
hypoxic-ischemic encephalopathy
oxidative stress
oxidative damage
Online Access:https://www.mdpi.com/2076-3921/10/10/1523

Internet

https://www.mdpi.com/2076-3921/10/10/1523

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