Transcriptomics reveal stretched human pluripotent stem cell-derived cardiomyocytes as an advantageous hypertrophy model

Left ventricular hypertrophy, characterized by hypertrophy of individual cardiomyocytes, is an adaptive response to an increased cardiac workload that eventually leads to heart failure. Previous studies using neonatal rat ventricular myocytes (NRVMs) and animal models have revealed several genes and...

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Bibliographic Details
Main Authors: Lotta Pohjolainen, Heikki Ruskoaho, Virpi Talman
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Journal of Molecular and Cellular Cardiology Plus
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2772976122000149