The Gene <i>paaZ</i> of the Phenylacetic Acid (PAA) Catabolic Pathway Branching Point and <i>ech</i> outside the PAA Catabolon Gene Cluster Are Synergistically Involved in the Biosynthesis of the Iron Scavenger 7-Hydroxytropolone in <i>Pseudomonas donghuensis</i> HYS

The Gene <i>paaZ</i> of the Phenylacetic Acid (PAA) Catabolic Pathway Branching Point and <i>ech</i> outside the PAA Catabolon Gene Cluster Are Synergistically Involved in the Biosynthesis of the Iron Scavenger 7-Hydroxytropolone in <i>Pseudomonas donghuensis</i> HYS

The newly discovered iron scavenger 7-hydroxytropolone (7-HT) is secreted by <i>Pseudomonas donghuensis</i> HYS. In addition to possessing an iron-chelating ability, 7-HT has various other biological activities. However, 7-HT’s biosynthetic pathway remains unclear. This study was the fir...

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Bibliographic Details
Main Authors: Panning Wang, Yaqian Xiao, Donghao Gao, Yan Long, Zhixiong Xie
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:International Journal of Molecular Sciences
Subjects:
<i>Pseudomonas donghuensis</i> HYS
7-hydroxytropolone
biosynthetic pathway
<i>orf17–21</i> (<i>paaEDCBA</i>)
<i>orf26</i> (<i>paaG</i>)
phenylacetic acid metabolic pathway
Online Access:https://www.mdpi.com/1422-0067/24/16/12632

Internet

https://www.mdpi.com/1422-0067/24/16/12632

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