An In Vivo Electroencephalographic Analysis of the Effect of Riluzole against Limbic and Absence Seizure and Comparison with Glutamate Antagonists

An In Vivo Electroencephalographic Analysis of the Effect of Riluzole against Limbic and Absence Seizure and Comparison with Glutamate Antagonists

Background: Riluzole (RLZ) has demonstrated neuroprotective effects in several neurological disorders. These neuroprotective effects seem to be mainly due to its ability to inhibit the excitatory glutamatergic neurotransmission, acting on different targets located both at the presynaptic and postsyn...

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Bibliographic Details
Main Authors: Rita Citraro, Francesca Bosco, Gianfranco Di Gennaro, Martina Tallarico, Lorenza Guarnieri, Luca Gallelli, Vincenzo Rania, Antonio Siniscalchi, Giovambattista De Sarro, Antonio Leo
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Pharmaceutics
Subjects:
excitatory neurotransmission
limbic seizure
absence epilepsy
glutamatergic antagonists
antiseizure medications
Riluzole
Online Access:https://www.mdpi.com/1999-4923/15/7/2006

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https://www.mdpi.com/1999-4923/15/7/2006

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