A novel mechanism for regulation of the type I IFN response by herpesvirus deconjugases

A novel mechanism for regulation of the type I IFN response by herpesvirus deconjugases

Upon infection, viral nucleic acids are recognized by germline-encoded pattern-recognition receptors (PRRs), and cytosolic retinoic acid-inducible gene I (RIG-I)-like helicases (RLHs) that initiate signaling pathways resulting in the production of type I IFN and pro-inflammatory cytokines. Binding o...

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Bibliographic Details
Main Authors: Soham Gupta, Päivi Ylä-Anttila, Maria G. Masucci
Format: Article
Language:English
Published: Shared Science Publishers OG 2018-04-01
Series:Microbial Cell
Subjects:
Epstein-Barr virus
Herpesvirus
deconjugase
RIG-I signalosome
type I IFN
Online Access:http://microbialcell.com/researcharticles/a-novel-mechanism-for-regulation-of-the-type-i-ifn-response-by-herpesvirus-deconjugases/

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http://microbialcell.com/researcharticles/a-novel-mechanism-for-regulation-of-the-type-i-ifn-response-by-herpesvirus-deconjugases/

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