Inhibition of Epstein-Barr Virus Lytic Reactivation by the Atypical Antipsychotic Drug Clozapine

Inhibition of Epstein-Barr Virus Lytic Reactivation by the Atypical Antipsychotic Drug Clozapine

Epstein&#8722;Barr virus (EBV), a member of the <i>Herpesviridae</i> family, maintains a lifelong latent infection in human B cells. Switching from the latent to the lytic phase of its lifecycle allows the virus to replicate and spread. The viral lytic cycle is induced in infected cu...

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Bibliographic Details
Main Authors: Abbie G. Anderson, Cullen B. Gaffy, Joshua R. Weseli, Kelly L. Gorres
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Viruses
Subjects:
Epstein–Barr virus
herpes viruses
lytic gene expression
Burkitt lymphoma cells
clozapine
antipsychotic drug
antiviral drug
Online Access:https://www.mdpi.com/1999-4915/11/5/450

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https://www.mdpi.com/1999-4915/11/5/450

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