An Uncalibrated Image-Based Visual Servo Strategy for Robust Navigation in Autonomous Intravitreal Injection

Autonomous intravitreal injection in ophthalmology is a challenging surgical task as accurate depth measurement is difficult due to the individual differences in the patient’s eye and the intricate light reflection or refraction of the eyeball, often requiring the surgeon to first preposition the en...

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Main Authors: Xiangdong He, Hua Luo, Yuliang Feng, Xiaodong Wu, Yan Diao
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Electronics
Subjects:
Online Access:https://www.mdpi.com/2079-9292/11/24/4184
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author Xiangdong He
Hua Luo
Yuliang Feng
Xiaodong Wu
Yan Diao
author_facet Xiangdong He
Hua Luo
Yuliang Feng
Xiaodong Wu
Yan Diao
author_sort Xiangdong He
collection DOAJ
description Autonomous intravitreal injection in ophthalmology is a challenging surgical task as accurate depth measurement is difficult due to the individual differences in the patient’s eye and the intricate light reflection or refraction of the eyeball, often requiring the surgeon to first preposition the end-effector accurately. Image-based visual servo (IBVS) control does not rely on depth information, exhibiting potential for addressing the issues mentioned above. Here we describe an enhanced IBVS strategy to achieve high performance and robust autonomous injection navigation. The radial basis function (RBF) kernel with strong learning capability and fast convergence is used to globally map the uncertain nonlinear strong coupling relationship in complex uncalibrated IBVS control. The Siamese neural network (SNN) is then used to compare and analyze the characteristic differences between the current and target poses, thus making an approximation of the mapping relationships between the image feature changes and the end-effector motion. Finally, a robust sliding mode controller (SMC) based on min–max robust optimization is designed to implement effective surgical navigation. Data from the simulation and the physical model experiments indicate that the maximum localization and attitude errors of the proposed method are 0.4 mm and 0.18°, exhibiting desirable accuracy with the actual surgery and robustness to disturbances. These results demonstrate that the enhanced strategy can provide a promising approach that can achieve a high level of autonomous intravitreal injection without a surgeon.
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spelling doaj.art-fc3670f991124a6fa051c3f9f97d49e72023-11-24T14:31:48ZengMDPI AGElectronics2079-92922022-12-011124418410.3390/electronics11244184An Uncalibrated Image-Based Visual Servo Strategy for Robust Navigation in Autonomous Intravitreal InjectionXiangdong He0Hua Luo1Yuliang Feng2Xiaodong Wu3Yan Diao4School of Mechanical Engineering, Sichuan University, Chengdu 610065, ChinaSchool of Mechanical Engineering, Sichuan University, Chengdu 610065, ChinaAier School of Ophthalmology, Central South University, Changsha 410000, ChinaSchool of Mechanical Engineering, Sichuan University, Chengdu 610065, ChinaSchool of Mechanical Engineering, Sichuan University, Chengdu 610065, ChinaAutonomous intravitreal injection in ophthalmology is a challenging surgical task as accurate depth measurement is difficult due to the individual differences in the patient’s eye and the intricate light reflection or refraction of the eyeball, often requiring the surgeon to first preposition the end-effector accurately. Image-based visual servo (IBVS) control does not rely on depth information, exhibiting potential for addressing the issues mentioned above. Here we describe an enhanced IBVS strategy to achieve high performance and robust autonomous injection navigation. The radial basis function (RBF) kernel with strong learning capability and fast convergence is used to globally map the uncertain nonlinear strong coupling relationship in complex uncalibrated IBVS control. The Siamese neural network (SNN) is then used to compare and analyze the characteristic differences between the current and target poses, thus making an approximation of the mapping relationships between the image feature changes and the end-effector motion. Finally, a robust sliding mode controller (SMC) based on min–max robust optimization is designed to implement effective surgical navigation. Data from the simulation and the physical model experiments indicate that the maximum localization and attitude errors of the proposed method are 0.4 mm and 0.18°, exhibiting desirable accuracy with the actual surgery and robustness to disturbances. These results demonstrate that the enhanced strategy can provide a promising approach that can achieve a high level of autonomous intravitreal injection without a surgeon.https://www.mdpi.com/2079-9292/11/24/4184visual servoneural networksliding mode control
spellingShingle Xiangdong He
Hua Luo
Yuliang Feng
Xiaodong Wu
Yan Diao
An Uncalibrated Image-Based Visual Servo Strategy for Robust Navigation in Autonomous Intravitreal Injection
Electronics
visual servo
neural network
sliding mode control
title An Uncalibrated Image-Based Visual Servo Strategy for Robust Navigation in Autonomous Intravitreal Injection
title_full An Uncalibrated Image-Based Visual Servo Strategy for Robust Navigation in Autonomous Intravitreal Injection
title_fullStr An Uncalibrated Image-Based Visual Servo Strategy for Robust Navigation in Autonomous Intravitreal Injection
title_full_unstemmed An Uncalibrated Image-Based Visual Servo Strategy for Robust Navigation in Autonomous Intravitreal Injection
title_short An Uncalibrated Image-Based Visual Servo Strategy for Robust Navigation in Autonomous Intravitreal Injection
title_sort uncalibrated image based visual servo strategy for robust navigation in autonomous intravitreal injection
topic visual servo
neural network
sliding mode control
url https://www.mdpi.com/2079-9292/11/24/4184
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