Integrative clinical and molecular analysis of advanced biliary tract cancers on immune checkpoint blockade reveals potential markers of response

Integrative clinical and molecular analysis of advanced biliary tract cancers on immune checkpoint blockade reveals potential markers of response

Abstract Background While there have been encouraging preliminary clinical results for immune checkpoint inhibitors (ICIs) in BTCs, it remains a challenge to identify the subset of patients who may benefit. In this study, we evaluated the efficacy of ICI treatment in patients with advanced BTCs, and...

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Bibliographic Details
Main Authors: Jingjing Li, Qing Wei, Xiaoying Wu, Jun Sima, Qi Xu, Mengmeng Wu, Fufeng Wang, Haibo Mou, Hanguang Hu, Jianguo Zhao, Da Li, Jinlin Hu, Lingnan Zhang, Xiu Zhu, Lei Chen, Cong Luo, Junrong Yan, Jiachen He, Yutong Ma, Yang Shao, Wei Wu, Jieer Ying
Format: Article
Language:English
Published: Wiley 2020-08-01
Series:Clinical and Translational Medicine
Subjects:
biliary tract cancer
immune checkpoint blockade
NGS
predictive biomarkers
Online Access:https://doi.org/10.1002/ctm2.118

Internet

https://doi.org/10.1002/ctm2.118

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