Delivery of pOXR1 through an injectable liposomal nanoparticle enhances spinal cord injury regeneration by alleviating oxidative stress

Delivery of pOXR1 through an injectable liposomal nanoparticle enhances spinal cord injury regeneration by alleviating oxidative stress

Oxidation resistance 1 (OXR1) is regarded as a critical regulator of cellular homeostasis in response to oxidative stress. However, the role of OXR1 in the neuronal response to spinal cord injury (SCI) remains undefined. On the other hand, gene therapy for SCI has shown limited success to date due i...

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Bibliographic Details
Main Authors: Jing Zhang, Yao Li, Jun Xiong, Helin Xu, Guanghen Xiang, Mingqiao Fan, Kailiang Zhou, Yutian Lin, Xiangxiang Chen, Lin Xie, Hongyu Zhang, Jian Wang, Jian Xiao
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2021-10-01
Series:Bioactive Materials
Subjects:
Gene therapy
OXR1
DNA condensed agent
Spinal cord injury
Oxidative stress
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X21000979

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http://www.sciencedirect.com/science/article/pii/S2452199X21000979

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