ITGB4 Deficiency in Airway Epithelium Aggravates RSV Infection and Increases HDM Sensitivity

ITGB4 Deficiency in Airway Epithelium Aggravates RSV Infection and Increases HDM Sensitivity

BackgroundThe heterogeneity of RSV-infected pathology phenotype in early life is strongly associate with increased susceptibility of asthma in later life. However, the inner mechanism of this heterogeneity is still obscure. ITGB4 is a down-regulated adhesion molecular in the airway epithelia of asth...

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Main Authors: Xizi Du, Lin Yuan, Ye Yao, Yu Yang, Kai Zhou, Xinyu Wu, Leyuan Wang, Ling Qin, Wenkai Li, Yang Xiang, Xiangping Qu, Huijun Liu, Xiaoqun Qin, Ming Yang, Chi Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
respiratory syncytial virus
asthma
ITGB4
airway epithelial cell
infection
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.912095/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.912095/full

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