Protein Tyrosine Phosphatase 1B Inhibitors from the Stems of Akebia quinata

PTP1B deficiency in mouse mammary tumor virus (MMTV)-NeuNT transgenic mice inhibited the onset of MMTV-NeuNT-evoked breast cancer, while its overexpression was observed in breast cancer. Thus, PTP1B inhibitors are considered chemopreventative agents for breast cancer. As part of our program to find...

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Bibliographic Details
Main Authors: Jin-Pyo An, Thi Kim Quy Ha, Jinwoong Kim, Tae Oh Cho, Won Keun Oh
Format: Article
Language:English
Published: MDPI AG 2016-08-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/21/8/1091