Comparison of Fucoidans from <i>Saccharina latissima</i> Regarding Age-Related Macular Degeneration Relevant Pathomechanisms in Retinal Pigment Epithelium

Comparison of Fucoidans from <i>Saccharina latissima</i> Regarding Age-Related Macular Degeneration Relevant Pathomechanisms in Retinal Pigment Epithelium

Fucoidans from brown algae are described as anti-inflammatory, antioxidative, and antiangiogenic. We tested two <i>Saccharina latissima</i> fucoidans (SL-FRO and SL-NOR) regarding their potential biological effects against age-related macular degeneration (AMD). Primary porcine retinal p...

Full description

Bibliographic Details
Main Authors: Philipp Dörschmann, Tabea Thalenhorst, Charlotte Seeba, Marie-Theres Tischhöfer, Sandesh Neupane, Johann Roider, Susanne Alban, Alexa Klettner
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:International Journal of Molecular Sciences
Subjects:
sulfated fucan
retinal pigment epithelium-specific 65 kDa protein (RPE65)
vascular endothelial growth factor (VEGF)
phagocytosis
gene expression
protectin (CD59)
Online Access:https://www.mdpi.com/1422-0067/24/9/7939

Internet

https://www.mdpi.com/1422-0067/24/9/7939

Similar Items