A Highly Sensitive Flow Cytometric Approach to Detect Rare Antigen-Specific T Cells: Development and Comparison to Standard Monitoring Tools

A Highly Sensitive Flow Cytometric Approach to Detect Rare Antigen-Specific T Cells: Development and Comparison to Standard Monitoring Tools

Personalized vaccines against patient-unique tumor-associated antigens represent a promising new approach for cancer immunotherapy. Vaccine efficacy is assessed by quantification of changes in the frequency and/or the activity of antigen-specific T cells. Enzyme-linked immunosorbent spot (ELISpot) a...

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Bibliographic Details
Main Authors: Meytal Dror Levinsky, Baruch Brenner, Michal Yalon, Zohar Levi, Zvi Livneh, Zoya Cohen, Tamar Paz-Elizur, Rachel Grossman, Zvi Ram, Ilan Volovitz
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Cancers
Subjects:
cancer
peptide vaccine
RNA vaccine
personalized cancer vaccine
cancer testis antigens
neoantigens
Online Access:https://www.mdpi.com/2072-6694/15/3/574

Internet

https://www.mdpi.com/2072-6694/15/3/574

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