Zolbetuximab for Claudin18.2-positive gastric or gastroesophageal junction cancer

Claudins (CLDNs) are a family of major membrane proteins that form components of tight junctions. In normal tissues, CLDNs seal the intercellular space in the epithelial sheets to regulate tissue permeability, paracellular transport, and signal transduction. Claudin18.2 (CLDN18.2), a member of the C...

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Bibliographic Details
Main Authors: Yohei Kubota, Kohei Shitara
Format: Article
Language:English
Published: SAGE Publishing 2024-01-01
Series:Therapeutic Advances in Medical Oncology
Online Access:https://doi.org/10.1177/17588359231217967