Robust phenotyping of highly multiplexed tissue imaging data using pixel-level clustering

Abstract While technologies for multiplexed imaging have provided an unprecedented understanding of tissue composition in health and disease, interpreting this data remains a significant computational challenge. To understand the spatial organization of tissue and how it relates to disease processes...

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Bibliographic Details
Main Authors: Candace C. Liu, Noah F. Greenwald, Alex Kong, Erin F. McCaffrey, Ke Xuan Leow, Dunja Mrdjen, Bryan J. Cannon, Josef Lorenz Rumberger, Sricharan Reddy Varra, Michael Angelo
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-40068-5