Inferring chromosomal instability from copy number aberrations as a measure of chromosomal instability across human cancers

Abstract Background Cancer is a complex disease that is the second leading cause of death in the United States. Despite research efforts, the ability to manage cancer and select optimal therapeutic responses for each patient remains elusive. Chromosomal instability (CIN) is primarily a product of se...

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Bibliographic Details
Main Authors: Sasha Taluri, Vishal H. Oza, Tabea M. Soelter, Jennifer L. Fisher, Brittany N. Lasseigne
Format: Article
Language:English
Published: Wiley 2023-12-01
Series:Cancer Reports
Subjects:
Online Access:https://doi.org/10.1002/cnr2.1902