Heterogeneous perception of the ethical legitimacy of unbalanced randomization by institutional review board members: a clinical vignette-based survey

Abstract Background Institutional review boards must guarantee the ethical acceptability of a randomized controlled trial before it is conducted. However, some may regard an unbalanced randomization ratio as reflecting an absence of uncertainty between the groups being compared. The objective was to...

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Bibliographic Details
Main Authors: Clarisse Dibao-Dina, Agnès Caille, Bruno Giraudeau
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Trials
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13063-018-2822-1