In Vitro and in Silico Analysis of Phytochemicals From Fallopia dentatoalata as Dual Functional Cholinesterase Inhibitors for the Treatment of Alzheimer’s Disease

In Vitro and in Silico Analysis of Phytochemicals From Fallopia dentatoalata as Dual Functional Cholinesterase Inhibitors for the Treatment of Alzheimer’s Disease

Current studies have found that butyrylcholinesterase (BuChE) replaces the biological function of acetylcholinesterase (AChE) in the late stage of Alzheimer’s disease. Species in the genus of Fallopia, rich in polyphenols with diverse chemical structures and significant biological activities, are co...

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Bibliographic Details
Main Authors: Yichuang Wu, Xiangdong Su, Jielang Lu, Meifang Wu, Seo Young Yang, Yang Mai, Wenbin Deng, Yongbo Xue
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Pharmacology
Subjects:
Fallopia dentatoalata
Alzheimer’s disease
cholinesterase (AChE, BChE)
polyphenols
phenylpropanoid sucrose esters
kinetic—spectrophotometric method
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.905708/full

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https://www.frontiersin.org/articles/10.3389/fphar.2022.905708/full

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